Monash Proteomics and Metabolomics Platform (MPMP) - Drug Target Identification Node

Overview

MPMP perform targeted and untargeted proteomics, lipidomics and metabolomics studies for a wide range of biomedical and pharmaceutical applications.

Capabilities

Untargeted proteomics (DIA, DDA, TMT), Phosphoproteomics, Drug Target Identification (Chemoproteomics), Cross-linking MS, Native Protein MS

Untargeted/semi-targeted metabolomics (polar or non-polar), Stable isotope tracing, SCFA analysis, Thiol analysis, Amino Acid analysis, Bile Acid analysis, Peptidomics, Targeted metabolomics

Untargeted/semi-targeted lipidomics, Lipid mediators, Sphingolipid analysis, SCFA analysis, Bile Acid analysis, Steroid analysis, Targeted Lipidomics

Equipment

LC-MS: Exploris 120 with Vanquish, and Q-Exactive Orbitrap with Dionex U3000. Established informatics workflows (IDEOM) and extensive metabolite library.

LC-MS: Orbitrap Astral, Q-Exactive HF Orbitrap with nano-LC. Established informatics workflows (Maxquant, Spectronaut, LFQAnalyst)

LC-MS: Exploris 120 with Vanquish, and Q-Exactive Orbitrap with Dionex U3000. Established informatics workflows (IDEOM and DIPL).

Access Information

Projects can be conducted on a fee-for-service, collaborative (cost-recovery) or self-user basis. For further details please visit: www.monash.edu/researchinfrastructure/mpmp

Contacts

Associate Professor Darren Creek
MPMP - Drug Target Identification Node Director - 03 9903 9249
darren.creek@monash.edu

Team Members

Dr Dovile Anderson
Metabolomics and Lipidomics
dovile.anderson@monash.edu

Dr Ghizal Siddiqui
Proteomics
ghizal.siddiqui@monash.edu

Images

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